I know this thread is a little old, but I'm new around here and maybe my impressions will be useful to someone anyway. I've got two GPS'es - a Magellan Meridian Gold portable that I got two years ago and a Garmin StreetPilot 2620 automotive unit that I got two months ago.
I am really a "Mac Person" and do some pretty advanced things on several machines including CAD, 3d modeling, computer animation, digital video, etc. Unfortunately there just isn't much support for GPS and mapping on the Mac however, so I have an old hand-me-down P2/400 that I use with the GPS'es. I have the general purpose DeLorme Topo USA and Nat'l Geographic Backroads Explorer. For the Magellan I have MapSend Streets and Mapsend Topo which can upload detailed maps to the handheld GPS. For the Garmin I have MapSource Topo in addition to City Navigator database for the entire US that is pre-loaded onto the 2620's microdrive.
Of all these my favorite (so far) is the Garmin MapSource Topo. The StreetPilot 2620 has a 2.5 GB internal drive (mine has a removable compact flash card, although evidently the newer units have non-removable drives) but there is around 500 MB free to upload other maps. There is a menu option on the GPS that lets you choose the mapset you want which I find really handy. The City Navigator maps support full auto-routing so you can just enter a starting point and destination and it will guide you. However the topo maps can't auto-route. Nevertheless, more often than not I work with the topo maps because they have a lot more interesting stuff in the database and are great when you wonder "what's that lake over there?" They really seem to have all the little sand roads and streams on them and the topo contours match the actual elevations measured by the GPS very well. The 2620 is also a real pleasure to use; it has a lot of user-customizable features, the color screen is really bright and readable in full sunlight and the touch-screen interface works very well.
On the trail I use the Magellan with its topo maps. They really aren't as nice as the Garmin maps. They use a less accurate system of mapping contours that doesn't give you a lot of useful feedback out in the pines. I was just recently at Forked River Mountain for example, and you would be hard-pressed to realize that it wasn't just a flat plain from the Magellan map. But the Garmin showed all the contour lines. Things like streams are also generally just skinny lines on the Magellan where the Garmin does a better job of showing the actual shape. The Garmin website has a neat feature where you can display their maps to see the amount of detail. If you go to this
link and pick one of the US Topo maps from the drop down menu you can navigate around in it.
Having said all this however, the Meridian is a nice solid unit that manages to keep satellites locked pretty well even under heavy tree cover. I imagine I'd be happier with the Meridian Color, but not enough so to spend for the upgrade. Now unfortunately the portable Garmins with color screens get expensive if you want more than 24 MB of memory (and I would). It's also unfortunate that they don't have memory card slots like the Meridian.
Anyhow, those are a few random thoughts for anyone thinking of getting a GPS or software. I think the StreetPilot 2620 is just terrific and I'm totally hooked on it. The 2610 is pretty much identical except it doesn't have the full US database pre-loaded on a microdrive. But with compact flash cards getting cheaper and cheaper, you can get your own 2GB card and load it from the included City Navigator disks and probably end up about the same. With the 2620 they don't include the PC software since everything is pre-loaded, I had to buy the topo maps separately but I think they're a "must have" if you want to explore the pines.